| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized HumanFGF2 Protein at 1 Mu g/mL (100 Mu L/well) can bind PTX3 with a linear range of 0.98-18.86 ng/mL. |
| Gene Symbol: | PTX3 |
| Gene ID: | 5806 |
| Uniprot ID: | PTX3_HUMAN |
| Immunogen Region: | Glu18-Ser381 |
| Immunogen: | Recombinant Human TSG-14/PTX3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu18-Ser381) of human Pentraxin 3/TSG-14 (Accession #NP_002843.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | ENSDDYDLMYVNLDNEIDNG LHPTEDPTPCACGQEHSEWD KLFIMLENSQMRERMLLQAT DDVLRGELQRLREELGRLAE SLARPCAPGAPAEARLTSAL DELLQATRDAGRRLARMEGA EAQRPEEAGRALAAVLEELR QTRADLHAVQGWAARSWLPA GCETAILFPMRSKKIFGSVH PVRPMRLESFSACIWVKATD VLNKTILFSYGTKRNPYEIQ LYLSYQSIVFVVGGEENKL |
| Function | Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. |
| Protein Name | Pentraxin-Related Protein Ptx3Pentaxin-Related Protein Ptx3Tumor Necrosis Factor Alpha-Induced Protein 5Tnf Alpha-Induced Protein 5Tumor Necrosis Factor-Inducible Gene 14 ProteinTsg-14 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Pentraxin-Related Protein Ptx3 proteinPentaxin-Related Protein Ptx3 proteinTumor Necrosis Factor Alpha-Induced Protein 5 proteinTnf Alpha-Induced Protein 5 proteinTumor Necrosis Factor-Inducible Gene 14 Protein proteinTsg-14 proteinPTX3 proteinTNFAIP5 proteinTSG14 protein |
Information sourced from Uniprot.org