Human TRPS1 protein (Recombinant) (N-GST & C-His) (STJP008824)

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STJP008824
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TRPS1-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TRPS1
Gene ID: 7227
Uniprot ID: TRPS1_HUMAN
Immunogen Region: Lys400-Gly460
Immunogen: Homo sapiens (Human)
Post Translational Modifications Sumoylated. Sumoylation in the repressor domain inhibits the transcription repression activity. Sumoylation on Lys-1201 is the major site. Appears to be sumoylated on multiple sites.
Function Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.
Protein Name Zinc Finger Transcription Factor Trps1
Tricho-Rhino-Phalangeal Syndrome Type I Protein
Zinc Finger Protein Gc79
Cellular Localisation Nucleus
Alternative Protein Names Zinc Finger Transcription Factor Trps1 protein
Tricho-Rhino-Phalangeal Syndrome Type I Protein protein
Zinc Finger Protein Gc79 protein
TRPS1 protein

Information sourced from Uniprot.org

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