Human TRPC6 (Transient Receptor Potential Cation Channel Subfamily C, Member 6) Sandwich ELISA Kit (STJE0012814)

Human TRPC6 (Transient Receptor Potential Cation Channel Subfamily C, Member 6) Sandwich ELISA Kit (STJE0012814)

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STJE0012814
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Short Description :This TRPC6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.129ng/mL
Detection Limit:0.312-20ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:TRPC6
Gene ID:7225
Uniprot ID:TRPC6_HUMAN
Sample Type:tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.
Post Translational Modifications Phosphorylated by FYN, leading to an increase of TRPC6 channel activity.
Function Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
Protein Name Short Transient Receptor Potential Channel 6
Trpc6
Transient Receptor Protein 6
Trp-6
Database Links Reactome: R-HSA-114508
Reactome: R-HSA-139853
Reactome: R-HSA-3295583
Reactome: R-HSA-418890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Short Transient Receptor Potential Channel 6 ELISA kit
Trpc6 ELISA kit
Transient Receptor Protein 6 ELISA kit
Trp-6 ELISA kit
TRPC6 ELISA kit
TRP6 ELISA kit
output

Information sourced from Uniprot.org

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