Human TRIM9 protein (Recombinant) (N-His) (STJP008281)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TRIM9-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TRIM9 |
| Gene ID | 114088 |
| Uniprot ID | TRIM9_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp541-Ala710 |
Additional Info
| Post Translational Modifications | Auto-ubiquitinated. Poly-ubiquitinated in cultured cells, whereas it is monoubiquitinated in vitro. |
| Function | E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim9Ring Finger Protein 91Ring-Type E3 Ubiquitin Transferase Trim9Tripartite Motif-Containing Protein 9 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCell ProjectionDendriteCytoplasmic VesicleSecretory VesicleSynaptic VesicleSynapseCytoskeletonEnriched At Synaptic Terminals Where It Exists In A Soluble Form And A Synaptic Vesicle-Associated FormAssociated With The CytoskeletonFound In Proximal Dendrites Of Pyramidal Neurons In The Cerebral Cortex And HippocampusAnd Purkinje Cells In The Cerebellum |
| Alternative Protein Names | E3 Ubiquitin-Protein Ligase Trim9 proteinRing Finger Protein 91 proteinRing-Type E3 Ubiquitin Transferase Trim9 proteinTripartite Motif-Containing Protein 9 proteinTRIM9 proteinKIAA0282 proteinRNF91 protein |
Information sourced from Uniprot.org