Human TRIM40 protein (Recombinant) (N-His) (STJP016050)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TRIM40-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | TRIM40 |
| Gene ID | 135644 |
| Uniprot ID | TRI40_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Leu258 |
Additional Info
| Function | E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response. Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation. Also promotes the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation. |
| Protein Name | E3 Ubiquitin Ligase Trim40Probable E3 Nedd8-Protein LigaseRing Finger Protein 35 |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | E3 Ubiquitin Ligase Trim40 proteinProbable E3 Nedd8-Protein Ligase proteinRing Finger Protein 35 proteinTRIM40 proteinRNF35 protein |
Information sourced from Uniprot.org