Human Trappin-2/Elafin protein (Recombinant) (His-Tag) (STJP018348)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Trappin-2/Elafin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PI3 |
| Gene ID | 5266 |
| Uniprot ID | ELAF_HUMAN |
| Accession Number | NP_002629 |
| Immunogen | Human |
| Immunogen Region | 23-117aa |
| Immunogen Sequence |
Additional Info
| Function | Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Has been shown to inhibit the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor and to produce a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1 (TRPV1). |
| Protein Name | ElafinElastase-Specific InhibitorEsiPeptidase Inhibitor 3Pi-3Protease Inhibitor Wap3Skin-Derived AntileukoproteinaseSkalpWap Four-Disulfide Core Domain Protein 14 |
| Database Links | Reactome: R-HSA-6803157Reactome: R-HSA-6809371 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Elafin proteinElastase-Specific Inhibitor proteinEsi proteinPeptidase Inhibitor 3 proteinPi-3 proteinProtease Inhibitor Wap3 proteinSkin-Derived Antileukoproteinase proteinSkalp proteinWap Four-Disulfide Core Domain Protein 14 proteinPI3 proteinWAP3 proteinWFDC14 protein |
Information sourced from Uniprot.org