Human Transcobalamin II protein (Recombinant) (STJP000470)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding mature chain of Human Transcobalamin II-TCII (GLU19-TRP427 ) including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Human Transcobalamin II-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity | The activity was tested by the ability of immobilized Recombinant Human CD320 to bind recombinant human TCII.The ED50 was calculated to be < 1ng/ml NA |
Target Information
| Gene Symbol | TCN2 |
| Gene ID | 6948 |
| Uniprot ID | TCO2_HUMAN |
| Immunogen | Optimized DNA sequence encoding mature chain of Human Transcobalamin II-TCII (GLU19-TRP427 ) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | GLU19-TRP427 |
Additional Info
| Function | Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. |
| Protein Name | Transcobalamin-2Tc-2Transcobalamin IiTc IiTcii |
| Database Links | Reactome: R-HSA-3359454Reactome: R-HSA-3359485Reactome: R-HSA-9758890 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Transcobalamin-2 proteinTc-2 proteinTranscobalamin Ii proteinTc Ii proteinTcii proteinTCN2 proteinTC2 protein |
Information sourced from Uniprot.org