| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Transcobalamin II-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: | The activity was tested by the ability of immobilized Recombinant Human CD320 to bind recombinant human TCII.The ED50 was calculated to be < 1ng/ml NA |
| Gene Symbol: | TCN2 |
| Gene ID: | 6948 |
| Uniprot ID: | TCO2_HUMAN |
| Immunogen Region: | GLU19-TRP427 |
| Immunogen: | Optimized DNA sequence encoding mature chain of Human Transcobalamin II-TCII (GLU19-TRP427 ) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Function | Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. |
| Protein Name | Transcobalamin-2Tc-2Transcobalamin IiTc IiTcii |
| Database Links | Reactome: R-HSA-3359454Reactome: R-HSA-3359485Reactome: R-HSA-9758890 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Transcobalamin-2 proteinTc-2 proteinTranscobalamin Ii proteinTc Ii proteinTcii proteinTCN2 proteinTC2 protein |
Information sourced from Uniprot.org
