Human TRAF5 protein (Recombinant) (N-His) (STJP003154)

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STJP003154
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TRAF5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TRAF5
Gene ID: 7188
Uniprot ID: TRAF5_HUMAN
Immunogen Region: Gln181-Arg437
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated at Lys-318 by the SCF(FBXL2) complex, leading to its degradation by the proteasome.
Function Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
Protein Name Tnf Receptor-Associated Factor 5
Ring Finger Protein 84
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Tnf Receptor-Associated Factor 5 protein
Ring Finger Protein 84 protein
TRAF5 protein
RNF84 protein

Information sourced from Uniprot.org