| Short Description : | Recombinant-Active-Human TPST1-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to transfer sulfate from PAPS to PSGL-1 peptide (Gln-Ala-Thr-Glu-Tyr-Glu-Tyr-Leu-Asp-Tyr-Asp-PheLeu-Pro-GluThr). The specific activity is >5 pmol/min/Mu g, as measured under the described conditions. |
| Gene Symbol: | TPST1 |
| Gene ID: | 8460 |
| Uniprot ID: | TPST1_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Gln26-Glu370 |
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. |
| Protein Name | Protein-Tyrosine Sulfotransferase 1Tyrosylprotein Sulfotransferase 1Tpst-1 |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-163841Reactome: R-HSA-9674519 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Protein-Tyrosine Sulfotransferase 1 proteinTyrosylprotein Sulfotransferase 1 proteinTpst-1 proteinTPST1 protein |
Information sourced from Uniprot.org
