| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. |
| Protein Name | Tryptase Alpha/Beta-1Tryptase-1Tryptase ITryptase Alpha-1 |
| Database Links | Reactome: R-HSA-1592389 |
| Cellular Localisation | SecretedReleased From The Secretory Granules Upon Mast Cell Activation |
| Alternative Protein Names | Tryptase Alpha/Beta-1 proteinTryptase-1 proteinTryptase I proteinTryptase Alpha-1 proteinTPSAB1 proteinTPS1 proteinTPS2 proteinTPSB1 protein |
Information sourced from Uniprot.org