Human TPM2 (Tropomyosin 2 Beta) Sandwich ELISA Kit Kit (STJE0012760)

Human TPM2 (Tropomyosin 2 Beta) Sandwich ELISA Kit Kit (STJE0012760)

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STJE0012760
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.247ng/mL
Detection Limit: 0.625-40ng/mL
Short Description : This TPM2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: TPM2
Gene ID: 7169
Uniprot ID: TPM2_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Present in primary breast cancer tissue, absent from normal breast tissue.
Post Translational Modifications Phosphorylated on Ser-61 by PIK3CG. Phosphorylation on Ser-61 is required for ADRB2 internalization.
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization.
Protein Name Tropomyosin Beta Chain
Beta-Tropomyosin
Tropomyosin-2
Database Links Reactome: R-HSA-390522
Reactome: R-HSA-445355
Cellular Localisation Cytoplasm
Cytoskeleton
Associates With F-Actin Stress Fibers
Alternative ELISA Names Tropomyosin Beta Chain ELISA kit
Beta-Tropomyosin ELISA kit
Tropomyosin-2 ELISA kit
TPM2 ELISA kit
TMSB ELISA kit
output

Information sourced from Uniprot.org

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