| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human TPH1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | TPH1 |
| Gene ID: | 7166 |
| Uniprot ID: | TPH1_HUMAN |
| Immunogen Region: | Met1-Ile444 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome. |
| Function | Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. |
| Protein Name | Tryptophan 5-Hydroxylase 1Tryptophan 5-Monooxygenase 1 |
| Database Links | Reactome: R-HSA-209931Reactome: R-HSA-9031628 |
| Alternative Protein Names | Tryptophan 5-Hydroxylase 1 proteinTryptophan 5-Monooxygenase 1 proteinTPH1 proteinTPH proteinTPRH proteinTRPH protein |
Information sourced from Uniprot.org
