| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | TNFSF9 |
| Gene ID: | 8744 |
| Uniprot ID: | TNFL9_HUMAN |
| Immunogen Region: | Arg71-Glu254 |
| Immunogen: | Recombinant Human TNFSF9/4-1BB Ligand Trimer Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Arg71-Glu254) of Human TNFSF9/4-1BB Ligand Trimer (Accession #P41273) fused with a N-monomeric hFc tag |
| Immunogen Sequence: | REGPELSPDDPAGLLDLRQG MFAQLVAQNVLLIDGPLSWY SDPGLAGVSLTGGLSYKEDT KELVVAKAGVYYVFFQLELR RVVAGEGSGSVSLALHLQPL RSAAGAAALALTVDLPPASS EARNSAFGFQGRLLHLSAGQ RLGVHLHTEARARHAWQLTQ GATVLGLFRVTPEIPAGLPS PRSE |
| Tissue Specificity | Expressed in brain, placenta, lung, skeletal muscle and kidney. |
| Function | Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 94-1bb Ligand4-1bbl |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Ligand Superfamily Member 9 protein4-1bb Ligand protein4-1bbl proteinTNFSF9 protein |
Information sourced from Uniprot.org
