Name: Human TNFSF15 protein (Recombinant) (No tag) (STJP000828)
SKU: STJP000828
Availability: InStock

Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of 20mM Tris, 50mM NaCl, 5% Glycerol, pH 8.0.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 1.0 EU/Mu g of the protein by LAL method.
Immunoreactivity:	1.Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF15 Protein at 5 Mu g/mL (100 Mu L/well) can bind DCR3 with a linear range of 0.12-6.98 ng/mL.\|2.Measured by its ability to induce apoptosis of TF‑1 human erythroleukemic

Gene Symbol:	TNFSF15
Gene ID:	9966
Uniprot ID:	TNF15_HUMAN
Immunogen Region:	Leu72-Leu251
Immunogen:	Active Recombinant Human TNFSF15 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Leu72-Leu251) of human TL1A/TNFSF15 (Accession #NP_005109.2) fused with an initial Met at the N-terminus.
Immunogen Sequence:	LKGQEFAPSHQQVYAPLRAD GDKPRAHLTVVRQTPTQHFK NQFPALHWEHELGLAFTKNR MNYTNKFLLIPESGDYFIYS QVTFRGMTSECSEIRQAGRP NKPDSITVVITKVTDSYPEP TQLLMGTKSVCEVGSNWFQP IYLGAMFSLQEGDKLMVNVS DISLVDYTKEDKTFFGAFLL

Tissue Specificity	Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
Function	Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Protein Name	Tumor Necrosis Factor Ligand Superfamily Member 15 Tnf Ligand-Related Molecule 1 Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form
Database Links	Reactome: R-HSA-5669034
Cellular Localisation	Membrane Single-Pass Type Ii Membrane Protein Tumor Necrosis Factor Ligand Superfamily Member 15 Secreted Form: Secreted
Alternative Protein Names	Tumor Necrosis Factor Ligand Superfamily Member 15 protein Tnf Ligand-Related Molecule 1 protein Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form protein TNFSF15 protein TL1 protein VEGI protein

Information sourced from Uniprot.org

Model	Name	Host
STJP002543	Human IgG3 protein (Recombinant) (No-Tag) (STJP002543)	HEK293 cells
STJP002542	Human IgG2A protein (Recombinant) (No-Tag) (STJP002542)	HEK293 cells
STJP000789	Human PIN1 protein (Recombinant) (No tag) (STJP000789)	E. coli
STJP000836	Human ISG15 protein (Recombinant) (No tag) (STJP000836)	E. coli

Human TNFSF15 protein (Recombinant) (No tag) (STJP000828)