| Host: |
E. coli |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human TNFSF15-No tag protein was developed from e. coli and has a target region of No tag. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of 20mM TRIS, 50mM NaCl, 5% Glycerol, pH 8.0. Contact us for customized product form or formulation. |
| Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF15 Protein at 5 Mu g/mL (100 Mu L/well) can bind DCR3 with a linear range of 0.12-6.98 ng/mL.2. Measured by its ability to induce apoptosis of TF‑1 human erythroleukemic ce |
| Gene Symbol: |
TNFSF15 |
| Gene ID: |
9966 |
| Uniprot ID: |
TNF15_HUMAN |
| Immunogen Region: |
Leu72-Leu251 |
| Immunogen: |
Active Recombinant Human TNFSF15 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Leu72-Leu251) of human TL1A/TNFSF15 (Accession #NP_005109.2) fused with an initial Met at the N-terminus. |
| Tissue Specificity | Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. |
| Function | Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 15Tnf Ligand-Related Molecule 1Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinTumor Necrosis Factor Ligand Superfamily Member 15Secreted Form: Secreted |
| Alternative Protein Names | Tumor Necrosis Factor Ligand Superfamily Member 15 proteinTnf Ligand-Related Molecule 1 proteinVascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form proteinTNFSF15 proteinTL1 proteinVEGI protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
