Human TNFRSF3/LTBR protein (Recombinant) (His-Tag) (STJP018987)

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STJP018987
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Short Description :Recombinant-Human TNFRSF3/LTBR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:LTBR
Gene ID:4055
Uniprot ID:TNR3_HUMAN
Accession Number:NP_002333.1
Immunogen:Human
Immunogen Region:28-227aa
Immunogen Sequence:SQPQAV PPYASENQTC RDQEKEYYEP QHRICCSRCP PGTYVSAKCS RIRDTVCATC AENSYNEHWN YLTICQLCRP CDPVMGLEEI APCTSKRKTQ CRCQPGMFCA AWALECTHCE LLSDCPPGTE AELKDEVGKG NNHCVPCKAG HFQNTSSPSA RCQPHTRCEN QGLVEAAPGT AQSDTTCKNP LEPLPPEMSG TMLM
Function Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 3
Lymphotoxin-Beta Receptor
Tumor Necrosis Factor C Receptor
Tumor Necrosis Factor Receptor 2-Related Protein
Tumor Necrosis Factor Receptor Type Iii
Tnf-Riii
Tnfr-Iii
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 3 protein
Lymphotoxin-Beta Receptor protein
Tumor Necrosis Factor C Receptor protein
Tumor Necrosis Factor Receptor 2-Related Protein protein
Tumor Necrosis Factor Receptor Type Iii protein
Tnf-Riii protein
Tnfr-Iii protein
LTBR protein
D12S370 protein
TNFCR protein
TNFR3 protein
TNFRSF3 protein

Information sourced from Uniprot.org

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