Post Translational Modifications | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated. |
Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 25Apo-3Apoptosis-Inducing Receptor AirApoptosis-Mediating Receptor Dr3Apoptosis-Mediating Receptor TrampDeath Receptor 3Lymphocyte-Associated Receptor Of DeathLardProtein WslProtein Wsl-1 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 9: Cell MembraneIsoform 11: Cell MembraneIsoform 3: SecretedIsoform 4: SecretedIsoform 5: SecretedIsoform 6: SecretedIsoform 7: SecretedIsoform 8: SecretedIsoform 10: SecretedIsoform 12: Secreted |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 25 proteinApo-3 proteinApoptosis-Inducing Receptor Air proteinApoptosis-Mediating Receptor Dr3 proteinApoptosis-Mediating Receptor Tramp proteinDeath Receptor 3 proteinLymphocyte-Associated Receptor Of Death proteinLard proteinProtein Wsl proteinProtein Wsl-1 proteinTNFRSF25 proteinAPO3 proteinDDR3 proteinDR3 proteinTNFRSF12 proteinWSL proteinWSL1 proteinUNQ455 proteinPRO779 protein |
Information sourced from Uniprot.org