Human TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B) Sandwich ELISA Kit Ready-To-Use Kit (STJE0006877)

Human TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B) Sandwich ELISA Kit Ready-To-Use Kit (STJE0006877)

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STJE0006877
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.063ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This TNFRSF1B Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: TNFRSF1B
Gene ID: 7133
Uniprot ID: TNR1B_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylated.mainly on serine residues and with a very low level on threonine residues. A soluble form (tumor necrosis factor binding protein 2) is produced from the membrane form by proteolytic processing.
Function Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 1b
Tumor Necrosis Factor Receptor 2
Tnf-R2
Tumor Necrosis Factor Receptor Type Ii
Tnf-Rii
Tnfr-Ii
P75
P80 Tnf-Alpha Receptor
Cd Antigen Cd120b
Etanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2
Tbp-2
Tbpii
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5669034
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Reactome: R-HSA-6798695
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Tumor Necrosis Factor-Binding Protein 2: Secreted
Alternative ELISA Names Tumor Necrosis Factor Receptor Superfamily Member 1b ELISA kit
Tumor Necrosis Factor Receptor 2 ELISA kit
Tnf-R2 ELISA kit
Tumor Necrosis Factor Receptor Type Ii ELISA kit
Tnf-Rii ELISA kit
Tnfr-Ii ELISA kit
P75 ELISA kit
P80 Tnf-Alpha Receptor ELISA kit
Cd Antigen Cd120b ELISA kit
Etanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2 ELISA kit
Tbp-2 ELISA kit
Tbpii ELISA kit
TNFRSF1B ELISA kit
TNFBR ELISA kit
TNFR2 ELISA kit
output

Information sourced from Uniprot.org

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