| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human TMOD1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | TMOD1 |
| Gene ID: | 7111 |
| Uniprot ID: | TMOD1_HUMAN |
| Immunogen Region: | Gly160-Gly349 |
| Immunogen: | Homo sapiens (Human) |
| Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. |
| Protein Name | Tropomodulin-1Erythrocyte TropomodulinE-Tmod |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | CytoplasmCytoskeletonIn Myofibrils With Sarcomeric StructureLocalizes To The Pointed End Of Actin Thin Filaments |
| Alternative Protein Names | Tropomodulin-1 proteinErythrocyte Tropomodulin proteinE-Tmod proteinTMOD1 proteinD9S57E proteinTMOD protein |
Information sourced from Uniprot.org