Human TMEM70 protein (Recombinant) (N-His-SUMO) (STJP008784)

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STJP008784
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TMEM70-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TMEM70
Gene ID: 54968
Uniprot ID: TMM70_HUMAN
Immunogen Region: Thr163-Lys260
Immunogen: Homo sapiens (Human)
Function Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis. In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies.
Protein Name Transmembrane Protein 70 - Mitochondrial
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Mostly Located Within The Inner Cristae Membrane
Alternative Protein Names Transmembrane Protein 70 - Mitochondrial protein
TMEM70 protein

Information sourced from Uniprot.org

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