Human TL1A/TNFSF15 protein (Recombinant) (His-Tag) (STJP017185)

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STJP017185
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Short Description :Recombinant-Human TL1A/TNFSF15-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Bioactivity
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.5) containing 0.15M NaCl, 40% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:< 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity:Measured by its binding ability in a functional ELISA with Human DR3/TNFRSF25
Gene Symbol:TNFSF15
Gene ID:9966
Uniprot ID:TNF15_HUMAN
Accession Number:NP_005109.2
Immunogen:Human
Immunogen Region:72-251aa
Immunogen Sequence:LKGQEFAPS HQQVYAPLRA DGDKPRAHLT VVRQTPTQHF KNQFPALHWE HELGLAFTKN RMNYTNKFLL IPESGDYFIY SQVTFRGMTS ECSEIRQAGR PNKPDSITVV ITKVTDSYPE PTQLLMGTKS VCEVGSNWFQ PIYLGAMFSL QEGDKLMVNV SDISLVDYTK EDKTFFGAFL L
Tissue Specificity Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
Function Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 15
Tnf Ligand-Related Molecule 1
Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form
Database Links Reactome: R-HSA-5669034
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Tumor Necrosis Factor Ligand Superfamily Member 15
Secreted Form: Secreted
Alternative Protein Names Tumor Necrosis Factor Ligand Superfamily Member 15 protein
Tnf Ligand-Related Molecule 1 protein
Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form protein
TNFSF15 protein
TL1 protein
VEGI protein

Information sourced from Uniprot.org

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