Tissue Specificity | Widely expressed. Expressed in endothelial cells and in peripheral neurons (at protein level). Isoform 3: Not expressed in fetal neocortex. Isoform 4: Expressed in fetal neocortex. |
Post Translational Modifications | |
Function | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Isoform 4: During fetal neocortex development, may be essential to maintain the full number of basal radial glia (bRG). bRG are neural progenitor cells that undergo asymmetric divisions, generating a bRG (self-renewal) and a neuron, in contrast to basal intermediate progenitors (bIPs), which typically divide once to give rise to 2 neurons. bRG generate more cortical neurons over time than bIPs. |
Protein Name | Transketolase-Like Protein 1Transketolase 2Tk 2Transketolase-Related Protein |
Database Links | |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Transketolase-Like Protein 1 ELISA kitTransketolase 2 ELISA kitTk 2 ELISA kitTransketolase-Related Protein ELISA kitTKTL1 ELISA kitTKR ELISA kitTKT2 ELISA kit |
output | |
Information sourced from Uniprot.org