Name: Human TIMP1 protein (Recombinant) (N-His) (STJP003508)
SKU: STJP003508
Availability: InStock

Human TIMP1 protein (Recombinant) (N-His) (STJP003508)

SKU:

STJP003508

$443.48 - $1,940.63

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human TIMP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	The activity of TIMP1 is dependent on the presence of disulfide bonds. N-glycosylated.
Function	Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro.but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
Protein Name	Metalloproteinase Inhibitor 1 Erythroid-Potentiating Activity Epa Fibroblast Collagenase Inhibitor Collagenase Inhibitor Tissue Inhibitor Of Metalloproteinases 1 Timp-1
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-1592389 Reactome: R-HSA-381426 Reactome: R-HSA-6783783 Reactome: R-HSA-6785807 Reactome: R-HSA-8957275 Reactome: R-HSA-9839383
Cellular Localisation	Secreted
Alternative Protein Names	Metalloproteinase Inhibitor 1 protein Erythroid-Potentiating Activity protein Epa protein Fibroblast Collagenase Inhibitor protein Collagenase Inhibitor protein Tissue Inhibitor Of Metalloproteinases 1 protein Timp-1 protein TIMP1 protein CLGI protein TIMP protein

Information sourced from Uniprot.org

Model	Name	Host
STJP009790	Mouse TIMP1 protein (Recombinant) (N-His) (STJP009790)	E. coli
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP011678	Human FSTL1 protein (Recombinant) (N-His) (STJP011678)	E. coli
STJP003644	Human ALDOA protein (Recombinant) (N-His) (STJP003644)	E. coli

Human TIMP1 protein (Recombinant) (N-His) (STJP003508)