Human Thymic stromal lymphopoietin/TSLP protein (Recombinant) (C-His&Avi) {Biotin} (STJP020123)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human Thymic stromal lymphopoietin/TSLP (R127A, R130A) Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Tyr29-Gln159 (R127A, R130A) ) of Human TSLP (R127A, R130A) fused with a H
General Information
| Short Description | Recombinant-Human Thymic stromal lymphopoietin/TSLP-C-His&Avi protein was developed in hek293 cells using the region R127A, R130A. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | TSLP |
| Gene ID | 85480 |
| Uniprot ID | TSLP_HUMAN |
| Immunogen | Biotinylated Recombinant Human Thymic stromal lymphopoietin/TSLP (R127A, R130A) Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Tyr29-Gln159 (R127A, R130A) ) of Human TSLP (R127A, R130A) fused with a H |
| Immunogen Region | R127A, R130A |
Additional Info
| Tissue Specificity | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. |
| Function | Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. |
| Protein Name | Thymic Stromal Lymphopoietin |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Thymic Stromal Lymphopoietin proteinTSLP protein |
Information sourced from Uniprot.org