Human THSD7A protein (Recombinant) (C-His) (STJP008660)

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STJP008660
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human THSD7A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: THSD7A
Gene ID: 221981
Uniprot ID: THS7A_HUMAN
Immunogen Region: Ala48-Trp1607
Immunogen: Homo sapiens (Human)
Post Translational Modifications Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form. Extensively N-glycosylated.
Function Thrombospondin type-1 domain-containing protein 7A: Plays a role in actin cytoskeleton rearrangement. Thrombospondin type-1 domain-containing protein 7A, soluble form: The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism.
Protein Name Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form
Database Links Reactome: R-HSA-5083635
Reactome: R-HSA-5173214
Cellular Localisation Thrombospondin Type-1 Domain-Containing Protein 7a: Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Detected On Podocyte Foot Processes
Thrombospondin Type-1 Domain-Containing Protein 7a
Soluble Form: Secreted
Proteolytic Cleavage In The Extracellular Region Generates A 210 Kda Soluble Form
Alternative Protein Names Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form protein
THSD7A protein
KIAA0960 protein

Information sourced from Uniprot.org