Tissue Specificity | Mostly in endothelial cells. |
Post Translational Modifications | O-glycosylated. |
Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
Protein Name | Tissue Factor Pathway InhibitorTfpiExtrinsic Pathway InhibitorEpiLipoprotein-Associated Coagulation InhibitorLaci |
Database Links | Reactome: R-HSA-140834 |
Cellular Localisation | Isoform Alpha: SecretedIsoform Beta: Microsome MembraneLipid-AnchorGpi-Anchor |
Alternative ELISA Names | Tissue Factor Pathway Inhibitor ELISA kitTfpi ELISA kitExtrinsic Pathway Inhibitor ELISA kitEpi ELISA kitLipoprotein-Associated Coagulation Inhibitor ELISA kitLaci ELISA kitTFPI ELISA kitLACI ELISA kitTFPI1 ELISA kit |
output | |
Information sourced from Uniprot.org