Human TFPI protein (Recombinant-Active) (C-His) (STJP011848)

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STJP011848-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human TFPI-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: TFPI
Gene ID: 7035
Uniprot ID: TFPI1_HUMAN
Immunogen Region: Asp29-Lys282
Immunogen: Homo sapiens (Human)
Post Translational Modifications O-glycosylated.
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Protein Name Tissue Factor Pathway Inhibitor
Tfpi
Extrinsic Pathway Inhibitor
Epi
Lipoprotein-Associated Coagulation Inhibitor
Laci
Database Links Reactome: R-HSA-140834
Cellular Localisation Isoform Alpha: Secreted
Isoform Beta: Microsome Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Protein Names Tissue Factor Pathway Inhibitor protein
Tfpi protein
Extrinsic Pathway Inhibitor protein
Epi protein
Lipoprotein-Associated Coagulation Inhibitor protein
Laci protein
TFPI protein
LACI protein
TFPI1 protein

Information sourced from Uniprot.org

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