Host: | HEK293 cells |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized human HGF at 5 Mu g/mL (100 Mu L/well) can bind human CLEC3B with a linear range of 0.05-5.91 Mu g/mL. |
Gene Symbol: | CLEC3B |
Gene ID: | 7123 |
Uniprot ID: | TETN_HUMAN |
Immunogen: | Recombinant Human Tetranectin/CLEC3B Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu22-Val202) of human Tetranectin (Accession #NP_003269.2) fused with a 6×His tag at the C-terminus. |
Immunogen Sequence: | EPPTQKPKKIVNAKKDVVNT KMFEELKSRLDTLAQEVALL KEQQALQTVCLKGTKVHMKC FLAFTQTKTFHEASEDCISR GGTLSTPQTGSENDALYEYL RQSVGNEAEIWLGLNDMAAE GTWVDMTGARIAYKNWETEI TAQPDGGKTENCAVLSGAAN GKWFDKRCRDQLPYICQFGI V |
Tissue Specificity | Found in plasma. |
Function | Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. Plays a role in retinal function. |
Protein Name | TetranectinTnC-Type Lectin Domain Family 3 Member BPlasminogen Kringle 4-Binding Protein |
Database Links | Reactome: R-HSA-114608 |
Cellular Localisation | Secreted |
Alternative Protein Names | Tetranectin proteinTn proteinC-Type Lectin Domain Family 3 Member B proteinPlasminogen Kringle 4-Binding Protein proteinCLEC3B proteinTNA protein |
Information sourced from Uniprot.org