Human TESPA1 protein (Recombinant) (N-His) (STJP011006)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TESPA1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TESPA1 |
| Gene ID | 9840 |
| Uniprot ID | TESP1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser148-Asp335 |
Additional Info
| Function | Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. |
| Protein Name | Protein Tespa1Thymocyte-Expressed Positive Selection-Associated Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmEndoplasmic Reticulum MembraneMay Localize To Mitochondria-Associated Endoplasmic Reticulum Membrane (Mam) |
| Alternative Protein Names | Protein Tespa1 proteinThymocyte-Expressed Positive Selection-Associated Protein 1 proteinTESPA1 proteinKIAA0748 proteinHSPC257 protein |
Information sourced from Uniprot.org