Human TESPA1 protein (Recombinant) (N-His) (STJP011006)

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STJP011006
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TESPA1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TESPA1
Gene ID: 9840
Uniprot ID: TESP1_HUMAN
Immunogen Region: Ser148-Asp335
Immunogen: Homo sapiens (Human)
Function Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
Protein Name Protein Tespa1
Thymocyte-Expressed Positive Selection-Associated Protein 1
Cellular Localisation Cytoplasm
Endoplasmic Reticulum Membrane
May Localize To Mitochondria-Associated Endoplasmic Reticulum Membrane (Mam)
Alternative Protein Names Protein Tespa1 protein
Thymocyte-Expressed Positive Selection-Associated Protein 1 protein
TESPA1 protein
KIAA0748 protein
HSPC257 protein

Information sourced from Uniprot.org

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