| Function | Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Seems to be directly involved in T-cell activation. |
| Protein Name | V-Type Proton Atpase 116 Kda Subunit A 3V-Atpase 116 Kda Subunit A 3Osteoclastic Proton Pump 116 Kda SubunitOc-116 KdaOc116T-Cell Immune Regulator 1T-Cell Immune Response Cdna7 ProteinTirc7Vacuolar Proton Translocating Atpase 116 Kda Subunit A Isoform 3 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-6798695Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | V-Type Proton Atpase 116 Kda Subunit A 3 proteinV-Atpase 116 Kda Subunit A 3 proteinOsteoclastic Proton Pump 116 Kda Subunit proteinOc-116 Kda proteinOc116 proteinT-Cell Immune Regulator 1 proteinT-Cell Immune Response Cdna7 Protein proteinTirc7 proteinVacuolar Proton Translocating Atpase 116 Kda Subunit A Isoform 3 proteinTCIRG1 proteinATP6N1C proteinATP6V0A3 protein |
Information sourced from Uniprot.org
