| Post Translational Modifications | Substrate of transglutaminase. Some 200 arginines are probably converted to citrullines by peptidylarginine deimidase. |
| Function | Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing during terminal differentiation. |
| Protein Name | Trichohyalin |
| Database Links | Reactome: R-HSA-6809371 |
| Alternative Protein Names | Trichohyalin proteinTCHH proteinTHH proteinTHL proteinTRHY protein |
Information sourced from Uniprot.org
