| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human TBR1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | TBR1 |
| Gene ID: | 10716 |
| Uniprot ID: | TBR1_HUMAN |
| Immunogen Region: | Lys203-Asn394 |
| Immunogen: | Homo sapiens (Human) |
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. |
| Protein Name | T-Box Brain Protein 1T-Brain-1Tbr-1Tes-56 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | T-Box Brain Protein 1 proteinT-Brain-1 proteinTbr-1 proteinTes-56 proteinTBR1 protein |
Information sourced from Uniprot.org
