| Tissue Specificity | Kidney and lung. Expressed in liver, with a strong circadian rhythmicity. Circadian expression is regulated by DBP. |
| Function | Highly active in the 15-alpha-hydroxylation of testosterone. Also active in the 15-alpha-hydroxylation of progesterone and androstenedione. Little or no activity on corticosterone, pregnenolone, dehydroepiandrosterone, estradiol or estriol. |
| Protein Name | Cytochrome P450 2a4Cypiia4Cytochrome P450-15-AlphaCytochrome P450-Iia3.1Testosterone 15-Alpha-Hydroxylase |
| Database Links | Reactome: R-MMU-211935Reactome: -MMU-211981Reactome: -MMU-211999 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
| Alternative Antibody Pair Names | Cytochrome P450 2a4 antibody pairCypiia4 antibody pairCytochrome P450-15-Alpha antibody pairCytochrome P450-Iia3.1 antibody pairTestosterone 15-Alpha-Hydroxylase antibody pairCyp2a4 antibody pairCyp2a-4 antibody pair |
Information sourced from Uniprot.org