Human SULT2B1 protein (Recombinant) (C-His) (STJP014251)

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STJP014251-100
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Host: E.coli
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SULT2B1-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 100mM NaCl, 1mM EDTA, pH 8.0.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: SULT2B1
Gene ID: 6820
Uniprot ID: ST2B1_HUMAN
Immunogen Region: Met1-Glu311
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it also has significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation. Isoform 2: Sulfonates pregnenolone but not cholesterol.
Protein Name Sulfotransferase 2b1
Alcohol Sulfotransferase
Hydroxysteroid Sulfotransferase 2
Sulfotransferase Family 2b Member 1
Sulfotransferase Family Cytosolic 2b Member 1
St2b1
Database Links Reactome: R-HSA-156584
Cellular Localisation Cytoplasm
Cytosol
Microsome
Nucleus
Phosphorylation Of Ser-348 Is Required For Translocation To The Nucleus
Alternative Protein Names Sulfotransferase 2b1 protein
Alcohol Sulfotransferase protein
Hydroxysteroid Sulfotransferase 2 protein
Sulfotransferase Family 2b Member 1 protein
Sulfotransferase Family Cytosolic 2b Member 1 protein
St2b1 protein
SULT2B1 protein
HSST2 protein

Information sourced from Uniprot.org

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