Human SULT1B1 protein (Recombinant) (N-His) (STJP010686)

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STJP010686
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SULT1B1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SULT1B1
Gene ID: 27284
Uniprot ID: ST1B1_HUMAN
Immunogen Region: Met1-Ile296
Immunogen: Homo sapiens (Human)
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system.
Protein Name Sulfotransferase 1b1
St1b1
Sulfotransferase 1b2
Sulfotransferase Family Cytosolic 1b Member 1
Thyroid Hormone Sulfotransferase
Database Links Reactome: R-HSA-156584
Cellular Localisation Cytoplasm
Alternative Protein Names Sulfotransferase 1b1 protein
St1b1 protein
Sulfotransferase 1b2 protein
Sulfotransferase Family Cytosolic 1b Member 1 protein
Thyroid Hormone Sulfotransferase protein
SULT1B1 protein
ST1B2 protein
SULT1B2 protein

Information sourced from Uniprot.org

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