Tissue Specificity | Expressed at highest levels in the ovary, skeletal muscle, stomach, brain, uterus, heart, kidney and placenta. |
Post Translational Modifications | Processing by furin produces a secreted form. Glycosylation at Ser-583 negatively regulates its N-acetylglucosamine-6-sulfatase and arylsulfatase activities. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
Function | Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. |
Protein Name | Extracellular Sulfatase Sulf-2Hsulf-2ArylsulfataseN-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form |
Database Links | |
Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusGolgi StackCell SurfaceExtracellular Sulfatase Sulf-2 Secreted Form: Secreted |
Alternative ELISA Names | Extracellular Sulfatase Sulf-2 ELISA kitHsulf-2 ELISA kitArylsulfatase ELISA kitN-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form ELISA kitSULF2 ELISA kitKIAA1247 ELISA kitUNQ559 ELISA kitPRO1120 ELISA kit |
output | |
Information sourced from Uniprot.org