Human SULF1 (Sulfatase 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018779)

Human SULF1 (Sulfatase 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018779)

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STJE0018779
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.62ng/mL
Detection Limit: 1.56-100ng/mL
Short Description : This SULF1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SULF1
Gene ID: 23213
Uniprot ID: SULF1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed at highest levels in testis, stomach, skeletal muscle, lung, kidney, pancreas, small intestine and colon. It is also detected in normal ovarian surface epithelial cells. Down-regulation seen in ovarian carcinoma cell lines, ovarian cancers, breast, pancreatic, renal and hepatocellular carcinoma cell lines.
Post Translational Modifications Processing by furin produces a secreted form. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Function Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation.
Protein Name Extracellular Sulfatase Sulf-1
Hsulf-1
Arylsulfatase
N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form
Database Links
Cellular Localisation Endoplasmic Reticulum
Golgi Apparatus
Golgi Stack
Cell Surface
Extracellular Sulfatase Sulf-2 Secreted Form: Secreted
Alternative ELISA Names Extracellular Sulfatase Sulf-1 ELISA kit
Hsulf-1 ELISA kit
Arylsulfatase ELISA kit
N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form ELISA kit
SULF1 ELISA kit
KIAA1077 ELISA kit
output

Information sourced from Uniprot.org

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