Human SULF1 protein (Recombinant) (N-GST) (STJP005676)

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STJP005676
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SULF1-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SULF1
Gene ID: 23213
Uniprot ID: SULF1_HUMAN
Immunogen Region: Pro609-Arg862
Immunogen: Homo sapiens (Human)
Post Translational Modifications Processing by furin produces a secreted form. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Function Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation.
Protein Name Extracellular Sulfatase Sulf-1
Hsulf-1
Arylsulfatase
N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form
Cellular Localisation Endoplasmic Reticulum
Golgi Apparatus
Golgi Stack
Cell Surface
Extracellular Sulfatase Sulf-2 Secreted Form: Secreted
Alternative Protein Names Extracellular Sulfatase Sulf-1 protein
Hsulf-1 protein
Arylsulfatase protein
N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form protein
SULF1 protein
KIAA1077 protein

Information sourced from Uniprot.org

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