Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human STMN3-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | STMN3 |
Gene ID: | 50861 |
Uniprot ID: | STMN3_HUMAN |
Immunogen Region: | Ala2-Ser60 |
Immunogen: | Homo sapiens (Human) |
Post Translational Modifications | N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15. |
Function | Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. |
Protein Name | Stathmin-3Scg10-Like Protein |
Cellular Localisation | Golgi ApparatusCell ProjectionGrowth ConeAxonCytoplasmCytosol |
Alternative Protein Names | Stathmin-3 proteinScg10-Like Protein proteinSTMN3 proteinSCLIP protein |
Information sourced from Uniprot.org