Human STK10 protein (Recombinant) (N-His) (STJP010765)

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STJP010765
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human STK10-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: STK10
Gene ID: 6793
Uniprot ID: STK10_HUMAN
Immunogen Region: Asp31-Gly321
Immunogen: Homo sapiens (Human)
Post Translational Modifications Autophosphorylates following homodimerization, leading to activation of the protein.
Function Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro.however such data require additional evidences in vivo.
Protein Name Serine/Threonine-Protein Kinase 10
Lymphocyte-Oriented Kinase
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Alternative Protein Names Serine/Threonine-Protein Kinase 10 protein
Lymphocyte-Oriented Kinase protein
STK10 protein
LOK protein

Information sourced from Uniprot.org

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