Human SSH2 (Slingshot Homolog 2) Sandwich ELISA Kit (STJE0012348)
SPECIFICATIONS
General Information
| Short Description | This SSH2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.113ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | SSH2 |
| Gene ID | 85464 |
| Uniprot ID | SSH2_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. Required for spermatogenesis. Involved in acrosome biogenesis, probably by regulating cofilin-mediated actin cytoskeleton remodeling during proacrosomal vesicle fusion and/or Golgi to perinuclear vesicle trafficking. |
| Protein Name | Protein Phosphatase Slingshot Homolog 2Ssh-Like Protein 2Ssh-2lHssh-2l |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionCytoplasmic VesicleSecretory VesicleAcrosomeColocalizes With Filamentous Actin In The Cytoplasm And The Cell Periphery |
| Alternative ELISA Names | Protein Phosphatase Slingshot Homolog 2 ELISA kitSsh-Like Protein 2 ELISA kitSsh-2l ELISA kitHssh-2l ELISA kitSSH2 ELISA kitKIAA1725 ELISA kitSSH2L ELISA kit |
| output |
Information sourced from Uniprot.org