Function | Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
Protein Name | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 25 Alpha-Sr2Sr Type 2Steroid 5-Alpha-Reductase 2S5ar 2Type Ii 5-Alpha Reductase |
Database Links | Reactome: R-HSA-193048 |
Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
Alternative Protein Names | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 protein5 Alpha-Sr2 proteinSr Type 2 proteinSteroid 5-Alpha-Reductase 2 proteinS5ar 2 proteinType Ii 5-Alpha Reductase proteinSRD5A2 protein |
Information sourced from Uniprot.org