Human SRD5A2 protein (Recombinant) (N-GST) (STJP004543)

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STJP004543
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SRD5A2-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SRD5A2
Gene ID: 6716
Uniprot ID: S5A2_HUMAN
Immunogen Region: His90-Phe254
Immunogen: Homo sapiens (Human)
Function Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Protein Name 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2
5 Alpha-Sr2
Sr Type 2
Steroid 5-Alpha-Reductase 2
S5ar 2
Type Ii 5-Alpha Reductase
Database Links Reactome: R-HSA-193048
Cellular Localisation Microsome Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum Membrane
Alternative Protein Names 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 protein
5 Alpha-Sr2 protein
Sr Type 2 protein
Steroid 5-Alpha-Reductase 2 protein
S5ar 2 protein
Type Ii 5-Alpha Reductase protein
SRD5A2 protein

Information sourced from Uniprot.org