Human SRA1 protein (Recombinant) (N-His) (STJP009719)

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STJP009719
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SRA1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SRA1
Gene ID: 10011
Uniprot ID: SRA1_HUMAN
Immunogen Region: Glu108-Ser236
Immunogen: Homo sapiens (Human)
Function Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
Protein Name Steroid Receptor Rna Activator 1
Steroid Receptor Rna Activator Protein
Srap
Cellular Localisation Nucleus
Cytoplasm
Alternative Protein Names Steroid Receptor Rna Activator 1 protein
Steroid Receptor Rna Activator Protein protein
Srap protein
SRA1 protein
PP7684 protein

Information sourced from Uniprot.org

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