| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human SPTBN1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | SPTBN1 |
| Gene ID: | 6711 |
| Uniprot ID: | SPTB2_HUMAN |
| Immunogen Region: | Met1-Ser278 |
| Immunogen: | Homo sapiens (Human) |
| Function | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function. |
| Protein Name | Spectrin Beta Chain - Non-Erythrocytic 1Beta-Ii SpectrinFodrin Beta ChainSpectrin - Non-Erythroid Beta Chain 1 |
| Database Links | Reactome: R-HSA-373753Reactome: R-HSA-375165Reactome: R-HSA-445095Reactome: R-HSA-5673001Reactome: R-HSA-6807878Reactome: R-HSA-9013420Reactome: R-HSA-9013424Reactome: R-HSA-9662360Reactome: R-HSA-9662361Reactome: R-HSA-9703465 |
| Cellular Localisation | CytoplasmCytoskeletonMyofibrilSarcomereM LineCytosolCell MembraneColocalizes With Ank2 In A Distinct Intracellular Compartment Of Neonatal CardiomyocytesIsoform 2: Cell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Protein Names | Spectrin Beta Chain - Non-Erythrocytic 1 proteinBeta-Ii Spectrin proteinFodrin Beta Chain proteinSpectrin - Non-Erythroid Beta Chain 1 proteinSPTBN1 proteinSPTB2 protein |
Information sourced from Uniprot.org