Human SPINK5 (Serine Peptidase Inhibitor Kazal Type 5) Sandwich ELISA Kit Kit (STJE0012311)

Human SPINK5 (Serine Peptidase Inhibitor Kazal Type 5) Sandwich ELISA Kit Kit (STJE0012311)

SKU:
STJE0012311
€581.88 - €795.63
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.116ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This SPINK5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: SPINK5
Gene ID: 11005
Uniprot ID: ISK5_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Highly expressed in the thymus and stratum corneum. Also found in the oral mucosa, parathyroid gland, Bartholin's glands, tonsils, and vaginal epithelium. Very low levels are detected in lung, kidney, and prostate.
Post Translational Modifications Proteolytically processed by furin in individual domains (D1, D5, D6, D8 through D11, and D9 through D15) exhibiting various inhibitory potentials for multiple proteases.
Function Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.
Protein Name Serine Protease Inhibitor Kazal-Type 5
Lympho-Epithelial Kazal-Type-Related Inhibitor
Lekti Cleaved Into - Hemofiltrate Peptide Hf6478 - Hemofiltrate Peptide Hf7665
Database Links Reactome: R-HSA-6809371
Reactome: R-HSA-9725554
Cellular Localisation Secreted
Alternative ELISA Names Serine Protease Inhibitor Kazal-Type 5 ELISA kit
Lympho-Epithelial Kazal-Type-Related Inhibitor ELISA kit
Lekti Cleaved Into - Hemofiltrate Peptide Hf6478 - Hemofiltrate Peptide Hf7665 ELISA kit
SPINK5 ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0012312 Mouse SPINK5 (Serine Peptidase Inhibitor Kazal Type 5) Sandwich ELISA Kit Kit (STJE0012312) Mouse ELISA
STJE0018698 Human SPINK5 (Serine Peptidase Inhibitor Kazal Type 5) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018698) Human ELISA
STJE0018699 Mouse SPINK5 (Serine Peptidase Inhibitor Kazal Type 5) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018699) Mouse ELISA
STJE0012310 Human SPINK1 (Serine Peptidase Inhibitor Kazal Type 1) Sandwich ELISA Kit Kit (STJE0012310) Human ELISA
STJE0018697 Human SPINK1 (Serine Peptidase Inhibitor Kazal Type 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018697) Human ELISA
!