Human SOX13 protein (Recombinant) (N-His-SUMO) (STJP008978)

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STJP008978
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SOX13-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SOX13
Gene ID: 9580
Uniprot ID: SOX13_HUMAN
Immunogen Region: Asn429-Asp490
Immunogen: Homo sapiens (Human)
Function Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells. Promotes brown adipocyte differentiation. Inhibitor of WNT signaling.
Protein Name Transcription Factor Sox-13
Islet Cell Antigen 12
Sry
Sex Determining Region Y-Box 13
Type 1 Diabetes Autoantigen Ica12
Database Links Reactome: R-HSA-3769402
Cellular Localisation Nucleus
Cytoplasm
Alternative Protein Names Transcription Factor Sox-13 protein
Islet Cell Antigen 12 protein
Sry protein
Sex Determining Region Y-Box 13 protein
Type 1 Diabetes Autoantigen Ica12 protein
SOX13 protein

Information sourced from Uniprot.org

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