Host: |
Mammalian Cells |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : |
Recombinant-Human SOST-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: |
SOST |
Gene ID: |
50964 |
Uniprot ID: |
SOST_HUMAN |
Immunogen Region: |
Gln24-Tyr213 |
Immunogen: |
Homo sapiens (Human) |
Function | Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. |
Protein Name | Sclerostin |
Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Protein Names | Sclerostin proteinSOST proteinUNQ2976 proteinPRO7455 proteinPRO7476 protein |
Information sourced from Uniprot.org