Human SNX17 (Sorting Nexin 17) Sandwich ELISA Kit Kit (STJE0012254)

Human SNX17 (Sorting Nexin 17) Sandwich ELISA Kit Kit (STJE0012254)

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STJE0012254
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.057ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This SNX17 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: SNX17
Gene ID: 9784
Uniprot ID: SNX17_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Protein Name Sorting Nexin-17
Database Links
Cellular Localisation Cytoplasm
Early Endosome
Cytoplasmic Vesicle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative ELISA Names Sorting Nexin-17 ELISA kit
SNX17 ELISA kit
KIAA0064 ELISA kit
output

Information sourced from Uniprot.org

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