| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human snRNP-E/SNRPE-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | 0 |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-154°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | SNRPE |
| Gene ID: | 6635 |
| Uniprot ID: | RUXE_HUMAN |
| Immunogen Region: | Gln16-Asn92 |
| Immunogen: | Homo sapiens (Human) |
| Function | Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing. |
| Protein Name | Small Nuclear Ribonucleoprotein ESnrnp-ESm Protein ESm-ESme |
| Database Links | Reactome: R-HSA-111367Reactome: R-HSA-191859Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-73856Reactome: R-HSA-77588Reactome: R-HSA-9754678 |
| Cellular Localisation | CytoplasmCytosolNucleusSmn-Mediated Assembly Into Core Snrnps Occurs In The Cytosol Before Smn-Mediated Transport To The Nucleus To Be Included In Spliceosomes |
| Alternative Protein Names | Small Nuclear Ribonucleoprotein E proteinSnrnp-E proteinSm Protein E proteinSm-E proteinSme proteinSNRPE protein |
Information sourced from Uniprot.org